NEMO Therapy In Cosmetic Surgery & Woundcare
Cosmetic Surgery The 2021 annual global survey published by the International Society of Aesthetic Plastic Surgery (ISAP) showed there was a notable 19.3% increase in procedures performed by plastic surgeons in 2021 with over 12.8 million surgical procedures and 17.5 million non-surgical treatments performed worldwide. This increase shows the recovery from 2020 which saw a drop of -1.8% in all procedures performed, most likely due to the COVID-19 pandemic. Liposuction was the most common cosmetic surgical procedure in 2021, which saw a 24.8% increase with more than 1.9 million procedures, overtaking breast augmentation. Access to this market should be simple because we are tapping into the cosmetic surgeon’s wish to increase revenue with value added services and the patient’s vanity to look better in the fastest possible time, with the least possible discomfort. We have designed an alternative sealing system specifically for use in cosmetic surgery where close contact with the head and neck is not desirable.



Wound Care
Our experience with elective cosmetic surgery began in 2012 with our cooperation with a cosmetic surgeon located in New Jersey. Since that time the results achieved in the practical application of NEMO therapy clearly demonstrate that it reduces inflammation, swelling and pain, enhances wound closure, and reduces scarring. In procedures involving autologous fat transfer NEMO therapy also significantly reduces loss of transferred fat and provides better outcomes. Such results were supported by independent research and other practical applications [13, 14, 15]. When administered immediately post-surgery a typical treatment program involving only three to five treatments has substantially reduced recovery times for both the intended procedures and incidental laser burns; decreased the degree and resolution time of post-surgical bruising; lessoned nausea caused by high doses of lidocaine; and dramatically increased yields of autologous fat transfers with virtually 100% survival. The procedures performed have included natural breast augmentation, facial and buttock laser fat injection sculpting, fat injection over breast implants, Smartlipo, fractional laser face resurfacing, laser cellulite removal, laser skin tightening, liposuction, rhinoplasty, and hair transplantation. All patients and all procedures have benefited from NEMO therapy. There have been no problems, complications, or cases of patient rejection of treatment.
In brief, with our work in “normal wounds” we have established that outcomes of hyperoxic therapy are highly dose (i.e., a function of oxygen pressure, treatment duration, and treatment frequency) dependent and that the oxygen dose-response relationship exhibits hormesis. Consequently, treatments at too high a dose have diminished effects, and research involving such situations has muddled understanding of what can be achieved with oxygen therapy in the treatment of so-called “normal wounds.”
During further literature review for our new publication on oxygen dose-response [4], results from early studies concerning the importance of oxygen in healing made it evident that optimal PO2s for healing uncompromised incisional wounds are achievable at 1 ATA. It was noted by Hunt et al for instance, that “in uncomplicated surgical incisional wounds possessing sufficient nutritive flow, the optimal oxygen tension for healing is probably passed when the oxygen treatment is extended to hyperbaric conditions.” [16].
Hair Transplant
The global hair transplant market is a separate leg of the cosmetic surgical industry. It was valued at £4.9 billion in 2021 and is projected to reach $30.13 billion by 2031 with an annual growth rate 20.4% [17]. Our interest in this market is to promote NEMO as an adjunct to improve outcomes. We have already seen benefit in a limited number of cases.
There are currently two market leaders: Hair Club and Bosley. Between them these companies have over 100 centres in the U.S., Puerto Rico, and Canada. Internationally these companies have a presence in 60 countries. Both are owned by the same Japanese company, Aderans Co Ltd., which acquired Hair Club in 2012 for $163 million.
Another major player is Restoration Robotics which markets the ARTAS robotic hair transplant system. RR merged with Venus Concepts in 2019. The company has multiple locations in north America and one or more locations in each of 23 other countries.
In addition to the clinics and surgeons dedicated to hair transplantation there are many other cosmetic surgeons who offer hair transplant as an element of their overall practice. The precise number of these latter practitioners has not been identified but it is believed to be significant.
The hair loss industry is a burgeoning market which presents NEMO with a significant opportunity in both the domestic and international markets. As the second leg of the cosmetic surgical industry, access to this market should also be simple because we are tapping into the cosmetic surgeon’s wish to increase revenue with value added services and the patient’s vanity to look better in the fastest possible time with the least possible discomfort.

TheResults
An example from a patient that underwent Lutronic Genius RF microneedling combined with the Evo fractional CO2 laser on 2/28/23. This patient did one hour of oxygen on each day of these photos, a total of 7 treatments.
Surgeon commented on success of procedure, healing outcome, and client satisfaction.
